Christine (1983)

Nerdy misfit student Arnie (Keith Gordon) buys "Christine", a 1958 Plymouth Fury with a history in which people tend to die in and around her. 

Pretty soon, Arnie becomes obsessed with the evil car, and even becomes slightly possessed by it. Christine then goes out on its own and kills the people who have given Arnie a hard time, eventually even going after his girlfriend (played by Alexandra Paul).

John Carpenter directed this film based on a Stephen King novel. John Stockwell played Gordon's best friend, and the baddies were William Ostrander, Malcolm Danare and Stuart Charno. 

Also with Robert Prosky (as a cantankerous garage owner), Harry Dean Stanton (wasted in a nothing part) and Christine Belford. 

Look for a young Kelly Preston in the small role of Roseanne, a high school student.